Article

Normative modeling of brain morphology reveals neuroanatomical heterogeneity and biological subtypes in major depressive disorder

2025-12-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Major Depressive Disorder (MDD) is characterized by high neurobiological heterogeneity, which hinders precise diagnosis and treatment. Traditional group-level neuroimaging analyses fail to capture individual differences, while normative modeling offer a promising approach to quantify individual deviations from healthy brain structure patterns, facilitating the identification...

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Literature Corpus work: fd798c58-4004-5a89-af26-c624dd8db012
DOI: 10.64898/2025.12.07.692810

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