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Article

White Matter Stratification in Depression Predicts Multidimensional Antidepressant Responses

2025-12-09

Abstract excerpt

<h4>Background</h4> Major depressive disorder (MDD) is clinically heterogeneous, posing a persistent challenge for personalized treatment. While neuroimaging offers a promising path, existing symptom-based stratification schemes have proven inadequate in predicting antidepressant response. Crucially, studies focusing on white matter (WM) heterogeneity — a potential source of neurobiological subtypes— have failed...

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Literature Corpus work
fd5f2614-de87-5b95-adf8-afffe273b82c
DOI
10.64898/2025.12.08.25341854
Open publication

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White Matter Stratification in Depression Predicts Multidimensional Antidepressant ResponsesDOI 10.64898/2025.12.08.25341854
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