Article

Mapping Neurophysiological Subtypes of Major Depressive Disorder Using Normative Models of the Functional Connectome

2023-02-14

Abstract excerpt

Major depressive disorder (MDD) is the most burdensome psychiatric disorder characterized by remarkably heterogeneous clinical phenotypes. It remains challenging to delineate the heterogeneity of neurobiological abnormalities underlying the clinical variance and, on this basis, to identify neurophysiological subtypes of MDD patients. Here, using a large multisite resting-state functional MRI data from 1,148 MDD pa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 28cb36d2-f078-53e7-8703-f14d93a6a721
DOI: 10.1101/2023.02.13.528399

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mapping Neurophysiological Subtypes of Major Depressive Disorder Using Normative Models of the Functional ConnectomeDOI 10.1101/2023.02.13.528399Read

Normative modeling of brain morphology reveals neuroanatomical heterogeneity and biological subtypes in major depressive disorderSemantic proximity Read

Individual Deviations from Normative Electroencephalographic Connectivity Predict Antidepressant ResponseSemantic proximity Read

Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depressionSemantic proximity Read

Reproducibility of functional brain alterations in major depressive disorder: evidence from a multisite resting-state functional MRI study with 1,434 individualsSemantic proximity Read

Multi-scale neural signatures of major depressive, anxiety, and stress-related disordersSemantic proximity Read

Resolving Heterogeneity in Major Depression: Overcoupling and Undercoupling Subtypes Exhibit Differential Treatment Response and Molecular PathwaysSemantic proximity Read

Multi-Scale Characterization of Distance-dependent Functional Dysconnections in Major Depressive Disorder Across Two Asian Cohorts: A Genomic, Neurochemical, and Cellular PerspectiveSemantic proximity Read

Common brain networks between major depressive disorder and symptoms of depression that are validated for independent cohortsSemantic proximity Read

Shared and unique imaging-derived endo-phenotypes of two typical antidepressant-applicative depressive patients.Semantic proximity Read

White Matter Stratification in Depression Predicts Multidimensional Antidepressant ResponsesSemantic proximity Read

Brain structural connectivity, anhedonia, and phenotypes of major depressive disorder: A structural equation model approach.Semantic proximity Read

ENIGMA MDD: Seven Years of Global Neuroimaging Studies of Major Depression through Worldwide Data SharingSemantic proximity Read