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Article

Profound and reproducible patterns of reduced regional gray matter characterize major depressive disorder

24 Jul 2019

Abstract excerpt

Reduced gray matter (GM) volume may represent a hallmark of major depressive disorder (MDD) neuropathology, typified by wide-ranging distribution of structural alteration. In the study, we aimed to replicate and extend our previous finding of profound and widespread GM loss in MDD, and evaluate the diagnostic accuracy of a structural biomarker derived from GM volume in an interconnected pattern across the brain....

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PMID: 31341158
DOI: 10.1038/s41398-019-0512-8

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