Article

Reactive Bergmann glia play a central role in Spinocerebellar ataxia inflammation via the JNK pathway

2022-07-02

Abstract excerpt

The spinocerebellar ataxias (SCAs) are devastating neurological diseases characterized by progressive cerebellar incoordination. While neurons bear the brunt of the pathology, a growing body of evidence suggests that glial cells are also affected. It has, however, been difficult to understand the role of glia, given the diversity of subtypes, each with their individual contributions to neuronal health. Using human...

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Literature Corpus work: fd6cec6e-5d47-5d46-8d68-1e31f1391695
DOI: 10.1101/2022.06.29.498121

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