Article

Compromised nuclear envelope integrity drives tumor cell invasion

2020-05-23

Abstract excerpt

While mutations leading to a fragile envelope of the cell nucleus are well known to cause diseases such as muscular dystrophies or accelerated aging, the pathophysiological consequences of the recently discovered mechanically induced nuclear envelope ruptures in cells harboring no mutation are less known. Here we show that repeated loss of nuclear envelope integrity in nuclei experiencing mechanical constraints pr...

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Identifiers and source

Literature Corpus work: fd6a76df-2227-5f21-9139-a61c467635ed
DOI: 10.1101/2020.05.22.110122

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