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Article

Predicting the impact of non-coding variants on DNA methylation.

Nucleic acids research - 20 Jun 2017

Zeng Haoyang, Gifford David K

Abstract excerpt

DNA methylation plays a crucial role in the establishment of tissue-specific gene expression and the regulation of key biological processes. However, our present inability to predict the effect of genome sequence variation on DNA methylation precludes a comprehensive assessment of the consequences of non-coding variation. We introduce CpGenie, a sequence-based framework that learns a regulatory code of DNA...

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Identifiers

PMID: 28334830
DOI: 10.1093/nar/gkx177
PMCID: PMC5499808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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