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Distribution and prognostic impact of LymphGen subtypes in Korean diffuse large B-cell lymphoma using clinical NGS panel.

Blood advances - 24 Mar 2026

Yim Jeemin, Lee Sungyoung, Kim Sehui, Han Bogyeong, Lim Sojung, Song Young Keun, Youk Jeonghwan, Bae Jeong Mo, Koh Jiwon, Lee Cheol, Kim Young A, Paik Jin Ho, Kim Tae Min, Yun Hongseok, Jeon Yoon Kyung

Abstract excerpt

ABSTRACT: Several molecular subclassifications of diffuse large B-cell lymphoma (DLBCL) with prognostic and therapeutic potential have been proposed; however, validation in diverse populations and real-world clinical settings remains limited. We investigated the genetic subtypes of Korean DLBCL using the LymphGen classifier and an institutionally developed 121-gene targeted next-generation sequencing (NGS) panel....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphoma, Large B-Cell, Diffuse

Republic of Korea

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Open in PubMed Open full text

Identifiers

PMID: 41544233
DOI: 10.1182/bloodadvances.2025017049
PMCID: PMC12995492

Genes

BCL2
MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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