Article
A review on architecture of the gag-pol ribosomal frameshifting RNA in human immunodeficiency virus: a variability survey of virus genotypes.
Journal of biomolecular structure & dynamics - 1 Jun 2017
Qiao Qi, Yan Yanhua, Guo Jinmei, Du Shuqiang, Zhang Jiangtao, Jia Ruyue, Ren Haimin, Qiao Yuanbiao, Li Qingshan
Abstract excerpt
Programmed '-1' ribosomal frameshifting is necessary for expressing the pol gene overlapped from a gag of human immunodeficiency virus. A viral RNA structure that requires base pairing across the overlapping sequence region suggests a mechanism of regulating ribosome and helicase traffic during expression. To get precise roles of an element around the frameshift site, a review on architecture of the frameshifting...
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