Article

Immunometabolic Trajectory Phenotypes Predict ICU-Acquired Infection and Mortality in Sepsis: A Multicenter Retrospective Cohort Study

2026-06-16

Abstract excerpt

<h4>Background: </h4> Standard sepsis risk stratification relies on static scores and single time-point biomarkers, failing to capture the temporal complexity of the host response. The dynamic interplay between immune dysregulation and metabolic distress remains poorly integrated into clinical phenotyping. We hypothesized that early longitudinal trajectories of these domains could reveal distinct immunometabolic p...

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Literature Corpus work: fd34de79-80e5-53b8-a97d-ffacf4fb093e
DOI: 10.20944/preprints202606.1222.v1

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