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Development and Validation of 72-Hour Fluid Balance Trajectory Subphenotypes and Prognosis in Sepsis: A Multicenter Cohort Study

2025-12-22

Abstract excerpt

<title>Abstract</title> <p>Background Fluid management in sepsis is controversial, and while persistent positive fluid balance is linked to adverse outcomes, the prognostic value of the temporal patterns (trajectories) of cumulative fluid balance (CFB) during the first 72 hours after sepsis diagnosis remains unclear. This study aimed to identify distinct subphenotypes based on 72-hour CFB trajectories in adult s...

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Literature Corpus work
4d28dab9-04e5-5b5a-b8e6-6ac1cdd4ffeb
DOI
10.21203/rs.3.rs-8247018/v1
Open publication

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Development and Validation of 72-Hour Fluid Balance Trajectory Subphenotypes and Prognosis in Sepsis: A Multicenter Cohort StudyDOI 10.21203/rs.3.rs-8247018/v1
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