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Article

Association between blood urea nitrogen trajectory phenotypes and prognosis in patients with sepsis: a multicenter retrospective cohort study.

BMC infectious diseases - 22 Apr 2026

Jiang Ying, Ding Huafeng, Li Xiangquan

Abstract excerpt

BACKGROUND: Sepsis exhibits substantial heterogeneity, and its stratification may facilitate precision medicine. Whether blood urea nitrogen (BUN) trajectories can be used for phenotyping sepsis patients remains unclear. METHODS: Sepsis patients meeting the criteria were included from the Medical Information Mart for Intensive Care IV (MIMIC-IV) and eICU Collaborative Research Database (eICU-CRD). Latent class...

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Identifiers

PMID: 42021220
DOI: 10.1186/s12879-026-13339-x
PMCID: PMC13235081

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