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Article

Novel cortisol trajectory sub-phenotypes in sepsis.

Critical care (London, England) - 3 Sept 2024

Leng Fei, Gu Zhunyong, Pan Simeng, Lin Shilong, Wang Xu, Zhong Ming, Song Jieqiong

Abstract excerpt

BACKGROUND: Sepsis is a heterogeneous syndrome. This study aimed to identify new sepsis sub-phenotypes using plasma cortisol trajectory. METHODS: This retrospective study included patients with sepsis admitted to the intensive care unit of Zhongshan Hospital Fudan University between March 2020 and July 2022. A group-based cortisol trajectory model was used to classify septic patients into different...

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Biomarkers
Hydrocortisone
Intensive Care Units
Phenotype
Proportional Hazards Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39227988
DOI: 10.1186/s13054-024-05071-2
PMCID: PMC11370002

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