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Article

Dynamic Lactate Trajectories Identify Nonlinear Mortality Thresholds and D istinct Risk Phenotypes in Sepsis

2026-06-28

Abstract excerpt

<title>Abstract</title> <p> Background Sepsis and severe infection are leading causes of mortality in intensive care units (ICUs). Although blood lactate is widely used for risk stratification, static measurements fail to capture dynamic metabolic recovery. This study aimed to identify 48-hour lactate trajectories, characterize their nonlinear relationship with 28-day mortality, and validate the prognostic util...

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Literature Corpus work
53c92018-10ce-54eb-8c81-fb40d167aeea
DOI
10.21203/rs.3.rs-9927458/v1
Open publication

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Dynamic Lactate Trajectories Identify Nonlinear Mortality Thresholds and D istinct Risk Phenotypes in SepsisDOI 10.21203/rs.3.rs-9927458/v1
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