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Article

Clinical phenotyping of septic shock with latent profile analysis: A retrospective multicenter study.

Journal of critical care - 1 Feb 2025

Liu Guanghao, Wu Ruoqiong, He Jun, Xu Yichang, Han Li, Yu Yingying, Zhu Haibo, Guo Yehan, Fu Hao, Chen Ting, Zheng Shixiang, Shen Xiaopei

Abstract excerpt

BACKGROUND: Septic shock (SS) is a highly fatal and heterogeneous syndrome. Identifying distinct clinical phenotypes provides valuable insights into the underlying pathophysiological mechanisms and may help to propose precise clinical management strategies. METHODS: Latent profile analysis (LPA), a model-based unsupervised method, was used for phenotyping in the MIMIC cohort, and the model was externally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39432929
DOI: 10.1016/j.jcrc.2024.154932

Genes

LPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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