Article
Dynamic biomarker profiling and phenotyping in burn sepsis: a retrospective cohort study using growth mixture modeling.
Frontiers in cellular and infection microbiology - 1 Jan 2026
Xu Pei, Lou Jiaqi, Kong Hong, Li Jiliang, Xiang Ziyi, Zhu Xiaoyu, Cui Shengyong, Huang Neng, Xu Sida, Le Xin, Fan Youfen, Jin Guoying
Abstract excerpt
Objective: To assess the dynamic prognostic value of multicategory biomarkers in burn sepsis and identify patient phenotypes based on their longitudinal trajectories. Methods: This retrospective cohort study included 712 adult patients with burn sepsis (Sepsis-3) admitted to a regional burn ICU (2022-2025). Seventeen biomarkers covering nutrition (albumin, ALB; prealbumin, PA; transferrin, TRF; nitrogen balance),...
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