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Current concepts and molecular pathology of neurodegenerative diseases

14 Nov 2024

Abstract excerpt

Neurodegenerative diseases are a pathologically, clinically and genetically diverse group of diseases characterised by selective dysfunction, loss of synaptic connectivity and neurodegeneration, and are associated with the deposition of misfolded proteins in neurons and/or glia. Molecular studies have highlighted the role of conformationally altered proteins in the pathogenesis of neurodegenerative diseases and...

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PMID: 39672768
DOI: 10.1016/j.pathol.2024.10.006

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