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Histone Deacetylase Inhibition and Dietary Short-Chain Fatty Acids

26 Dec 2011

Abstract excerpt

Changes in diet can also have dramatic effects on the composition of gut microbiota. Commensal bacteria of the gastrointestinal tract are critical regulators of health and disease by protecting against pathogen encounter whilst also maintaining immune tolerance to certain allergens. Moreover, consumption of fibre and vegetables typical of a non-Western diet generates substantial quantities of short-chain fatty...

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PMID: 23724235
DOI: 10.5402/2011/869647

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