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Unraveling the Potential of ALK-Targeted Therapies in NSCLC: Comprehensive Insights and Future Directions

2024-01-08

Abstract excerpt

The current review comprehensively explores the multifaceted landscape of anaplastic lymphoma kinase (ALK) and its pivotal role, specifically within non-small cell lung cancer (NSCLC). It traces the trajectory of ALK's discovery, notably its fusion with nucleolar phosphoprotein (NPM)-1 in anaplastic large cell non-Hodgkin's lymphoma (ALCL) in 1994. It unfolds the subsequent impact of ALK gene alterations...

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Literature Corpus work
fcdc8636-adcd-5e19-afab-108b941b4fd8
DOI
10.20944/preprints202401.0541.v1
Open publication

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