Article
NSCLC: from tumorigenesis, immune checkpoint misuse to current and future targeted therapy
7 Feb 2024
Abstract excerpt
Non-small cell lung cancer (NSCLC) is largely promoted by a multistep tumorigenesis process involving various genetic and epigenetic alterations, which essentially contribute to the high incidence of mortality among patients with NSCLC. Clinical observations revealed that NSCLC also co-opts a multifaceted immune checkpoint dysregulation as an important driving factor in NSCLC progression and development. For...
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