Article
[Isocitrate dehydrogenase type I mutation as a prognostic factor in glioblastoma and a literature review].
Neurocirugia (Asturias, Spain) - 1 Jan 2000
de Quintana-Schmidt Cristian, Alvarez-Holzapfel María Jesús, Nomdedeu-Guinot Josep, Bague-Rosell Silvia, Gallego-Rubio Oscar, Leidinger Andreas, Salgado-Lopez Laura, Molet-Teixidó Joan
Abstract excerpt
OBJECTIVE: Treatment response and prognosis in glioblastoma (GBM) tumours can differ among patients, highlighting the growing relevance of genetic biomarkers to differentiate glioblastoma sub-types. The biomarker isocitrate dehydrogenase (IDH1) is currently receiving considerable attention. The objective of this work was to analyse the clinical and prognostic differences between glioblastomas with and without the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
