Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IDH mutation and MGMT methylation status in glioblastoma and other gliomas patients: a Russian retrospective cohort study.

Journal of the Egyptian National Cancer Institute - 16 May 2025

Eid Moez, Alset Dema, Timoshkina Nataliya, Gvaldin Dmitriy, Rostorguev Eduard, Kavitskiy Sergey, Novikova Inna

Abstract excerpt

Glioma is a devastating type of brain tumor with high malignancy, an extremely high mortality rate, and a recurrence risk. Molecular markers are known to have a major role in classification, prognosis, survival rate, and therapy determination for different glioma subtypes. The aim of this study was to investigate the association of gliomas' main genetic markers: isocitrate dehydrogenase (IDH) mutations and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair Enzymes

Share to Glioblastoma

Share to Glioma

Share to Isocitrate Dehydrogenase

Share to Russia

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 40377745
DOI: 10.1186/s43046-025-00296-w
PMCID: PMC13313434

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IDH mutation and MGMT methylation status in glioblastoma and other gliomas patients: a Russian retrospective cohort study.PMID 40377745Read ↗

IDH1/IDH2 mutations define the prognosis and molecular profiles of patients with gliomas: a meta-analysis.Semantic proximity Read ↗

Isocitrate Dehydrogenase Mutations are Better Prognostic Marker than O6-methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastomas - a Retrospective, Single-centre Molecular Genetics Study of Gliomas.Semantic proximity Read ↗

IDH1/2 Mutation and MGMT Promoter Methylation - the Relevant Survival Predictors in Czech Patients with Brain Gliomas.Semantic proximity Read ↗

Clinical Impact of IDH1 Mutations and MGMT Methylation in Adult GlioblastomaSemantic proximity Read ↗

Impact of IDH mutation and MGMT methylation as Independent prognostic markers in uniformly treated high grade glioma Patients: A Real-World evidence in the Indian Population.Semantic proximity Read ↗

Clinical Impact of <i>IDH1</i> Mutations and <i>MGMT</i> Methylation in Adult Glioblastoma MultiformeSemantic proximity Read ↗

Molecular classification of IDH-mutant glioblastomas based on gene expression profilesSemantic proximity Read ↗

The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations.Semantic proximity Read ↗

Isocitrate Dehydrogenase-1 Mutations as Prognostic Biomarker in Glioblastoma Multiforme Patients in West BohemiaSemantic proximity Read ↗

Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation.Semantic proximity Read ↗

Integrated Analysis of the Clinical and Molecular Characteristics of IDH Wild-Type Gliomas in the Chinese Glioma Genome AtlasSemantic proximity Read ↗

Genetic and clinical characteristics of primary and secondary glioblastoma is associated with differential molecular subtype distribution.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.