Article

A scalable screening platform for phenotypic subtyping of ALS patient-derived fibroblasts

2022-09-28

Abstract excerpt

<h4>ABSTRACT</h4> A major challenge for understanding and treating Amyotrophic Lateral Sclerosis (ALS) is that most patients have no known genetic cause. Even within defined genetic subtypes, patients display considerable clinical heterogeneity. It is unclear how to identify subsets of ALS patients that share common molecular dysregulation or could respond similarly to treatment. Here, we developed a scalable mic...

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Literature Corpus work: fc786e71-02a1-5b9e-848d-0f41d89e2930
DOI: 10.1101/2022.09.27.509770

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