Article

Automated and unbiased classification of motor neuron phenotypes with single cell resolution in ALS tissue

2020-08-17

Abstract excerpt

<h4>SUMMARY</h4> Histopathological analysis of tissue sections is an invaluable resource in neurodegeneration research. Importantly, cell-to-cell variation in both the presence and severity of a given phenotype is however a key limitation of this approach, reducing the signal to noise ratio and leaving unresolved the potential of single-cell scoring for a given disease attribute. Here, we developed an image proce...

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Literature Corpus work: f53b04f9-a255-5b0d-b73c-8e735c647e0e
DOI: 10.1101/2020.08.17.253773

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