Article

Interpreting GC content differences across populations at polymorphic sites

2026-05-18

Abstract excerpt

Recent studies have reported consistent inter-population differences in GC content at polymorphic sites in multiple species, including humans. Specifically, populations that experienced recent bottlenecks exhibit lower average GC content (GC%) at common polymorphic sites compared to non-bottlenecked groups—an observation previously interpreted as indication of rapid evolution of base composition. In this study, we...

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Literature Corpus work: fc6ba561-0eaa-5f7d-a5e0-ffdb7fac2806
DOI: 10.64898/2026.05.16.725686

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