Article

Tuning Parameters for Polygenic Risk Score Methods Using GWAS Summary Statistics from Training Data

2023-05-31

Abstract excerpt

<title>Abstract</title> <p>Predicting genetic risks for common diseases may improve their prevention and early treatment. In recent years, various additive-model-based polygenic risk scores (PRS) methods have been proposed to combine the estimated effects of single nucleotide polymorphisms (SNPs) using data collected from genome-wide association studies (GWAS). Some of these methods require access to another exte...

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Literature Corpus work: fc585373-1c95-522e-a507-63e65615ea2e
DOI: 10.21203/rs.3.rs-2939390/v1

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