Article

The role of dendritic brain-derived neurotrophic factor transcripts on altered inhibitory circuitry in depression

2018-05-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> A parallel downregulation of brain-derived neurotrophic factor ( BDNF ) and somatostatin ( SST ), a marker of inhibitory γ-amino-butyric acid (GABA) interneurons which target pyramidal cell dendrites, has been reported in several brain areas of subjects with major depressive disorder (MDD), and rodent genetic studies suggests they are linked and both contribute to the illn...

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Literature Corpus work: fc545bdf-976c-5b46-9b14-739f1babc5f4
DOI: 10.1101/333294

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