Article

Synergy of HLA class I and II shapes the timing of antitumor immune response

2022-11-17

Abstract excerpt

The presentation of mutated cancer peptides to T cells by human leukocyte antigen (HLA) class I and II molecules is necessary for antitumor immune response. Both classes are diverse and the variants have distinct peptide-binding specificities. HLA class I diversity was suggested to influence antitumor immunity, however, the findings are controversial. We examined the joint effect of the two HLA classes in melanoma...

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Literature Corpus work: fc41e9dc-fde9-5e19-bf67-bee737154f0b
DOI: 10.1101/2022.11.16.516740

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