Article

The bromodomain protein Bdf3 is sufficient to activate expression of a procyclin gene in bloodstream stage African trypanosomes

2026-01-12

Abstract excerpt

The early branching eukaryotic parasite, Trypanosoma brucei , lives extracellularly in the mammalian host, where it expresses variant surface glycoprotein (VSG). Antigenic variation of VSGs allows the parasite to evade the host immune response while in the bloodstream. Upon transition to the tsetse fly vector, the parasite remodels its surface to express procyclin protein from a limited set of EP and GPEET gene...

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Literature Corpus work: fc0e94ca-bf24-5ee8-b3e3-6e42e20b6734
DOI: 10.64898/2026.01.12.698981

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