Article
Functional impact bias reveals cancer drivers.
Nucleic acids research - 1 Nov 2012
Gonzalez-Perez Abel, Lopez-Bigas Nuria
Abstract excerpt
Identifying cancer driver genes and pathways among all somatic mutations detected in a cohort of tumors is a key challenge in cancer genomics. Traditionally, this is done by prioritizing genes according to the recurrence of alterations that they bear. However, this approach has some known limitat...
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