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The Disease-Associated Proteins <i>Drosophila</i> Nab2 and Ataxin-2 Interact with Shared RNAs and Coregulate Neuronal Morphology

2021-03-02

Abstract excerpt

<h4>ABSTRACT</h4> Nab2 encodes a conserved polyadenosine RNA-binding protein (RBP) with broad roles in post-transcriptional regulation, including in poly(A) RNA export, poly(A) tail length control, transcription termination, and mRNA splicing. Mutation of the Nab2 human ortholog ZC3H14 gives rise to an autosomal recessive intellectual disability, but understanding of Nab2/ZC3H14 function in metazoan nervous sys...

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Literature Corpus work
fbdb2da3-ce4b-552d-92a3-5f4c24fd6d9e
DOI
10.1101/2021.03.01.433469
Open publication

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The Disease-Associated Proteins <i>Drosophila</i> Nab2 and Ataxin-2 Interact with Shared RNAs and Coregulate Neuronal MorphologyDOI 10.1101/2021.03.01.433469
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