Article

The Nab2 RNA binding protein promotes sex-specific splicing of <i>Sex lethal</i> in <i>Drosophila</i> neuronal tissue

2020-11-14

Abstract excerpt

The Drosophila polyadenosine RNA binding protein Nab2, which is orthologous to a human protein lost in a form of inherited intellectual disability, controls axon projection, locomotion, and memory. Here we define an unexpectedly specific role for Nab2 in regulating splicing of ∼150 exons/introns in the head transcriptome and link the most prominent of these, female retention of a male-specific exon in the sex det...

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Literature Corpus work: 05b3c282-08e7-52e4-89de-d88ce453706f
DOI: 10.1101/2020.11.13.382168

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