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Article

Ataxin-2: a powerful RNA-binding protein

22 Jul 2024

Abstract excerpt

Ataxin-2 (ATXN2) was originally discovered in the context of spinocerebellar ataxia type 2 (SCA2), but it has become a key player in various neurodegenerative diseases. This review delves into the multifaceted roles of ATXN2 in human diseases, revealing its diverse molecular and cellular pathways. The impact of ATXN2 on diseases extends beyond functional outcomes; it mainly interacts with various RNA-binding...

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PMID: 39039334
DOI: 10.1007/s12672-024-01158-y

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