Article

Cell-Type Specific Single-Cell Signatures Reveal Nephrotoxic Drug Affects

2025-06-22

Abstract excerpt

Drug-induced acute kidney injury (AKI) affects about 20% of hospitalized AKI patients, a significant contributor to morbidity and mortality. The lack of understanding of the kidney system and functioning of nephrotoxic drugs contributes to hospital-acquired AKI cases. AKI is difficult to predict because of its complex injury mechanism and the numerous pathways through which it manifests. Traditional toxicity bioma...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4119ed96-390b-5813-ada1-34c50a39e337
DOI: 10.1101/2025.06.17.660070

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cell-Type Specific Single-Cell Signatures Reveal Nephrotoxic Drug AffectsDOI 10.1101/2025.06.17.660070Read

Transcriptomic responses of the human kidney to acute injury at single cell resolutionSemantic proximity Read

Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injurySemantic proximity Read

Urinary single-cell sequencing captures intrarenal injury and repair processes in human acute kidney injurySemantic proximity Read

Single-Cell RNA Sequencing of Urinary Cells Reveals Distinct Cellular Diversity in COVID-19–Associated AKISemantic proximity Read

Single Nucleus RNA Sequencing of Remnant Kidney Biopsies and Urine Cell RNA Sequencing Reveal Cell Specific Markers of Covid-19 Acute Kidney InjurySemantic proximity Read

Acute kidney injury subphenotyping and personalized medicine.Semantic proximity Read

Single-cell RNA sequencing reveals the transcriptomic landscape of kidneys in patients with ischemic acute kidney injurySemantic proximity Read

Single-cell transcriptomics: a novel precision medicine technique in nephrologySemantic proximity Read

Translating Knowledge Into Therapy for Acute Kidney Injury.Semantic proximity Read

Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to InjurySemantic proximity Read

The Recent Evolution of the Application of Single-Cell Analysis in Kidney Diseases: A bibliometric analysisSemantic proximity Read

Applying single-cell technologies to clinical pathology: progress in nephropathology.Semantic proximity Read