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Single-cell transcriptomics reveal the crosstalk between platelet-associated TRAF4high endothelial cell subpopulation and tumor microenvironment in colorectal cancer

2024-07-23

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<title>Abstract</title> <p>Background Platelet-tumor endothelial cell interactions are pivotal in the colorectal cancer microenvironment, driving tumor invasion, metastasis and shaping the immune landscape. Investigating these interactions sheds light on the underlying mechanisms of colorectal cancer progression and opens avenues for novel therapeutic interventions. Methods By interrogating 10x Genomics single-...

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Literature Corpus work
fb90b97d-104d-5a31-a328-e0693cbde478
DOI
10.21203/rs.3.rs-4506500/v1
Open publication

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Single-cell transcriptomics reveal the crosstalk between platelet-associated TRAF4high endothelial cell subpopulation and tumor microenvironment in colorectal cancerDOI 10.21203/rs.3.rs-4506500/v1
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