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Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women with Alzheimer’s Disease

2020-04-25

Abstract excerpt

<h4>ABSTRACT</h4> In spite of evidence of females having a greater lifetime risk of developing Alzheimer’s Disease (AD) and greater apolipoprotein E4-related (apoE4) AD risk compared to males, molecular signatures underlying these findings remain elusive. We took a meta-analysis approach to study gene expression in the brains of 1,084 AD patients and age-matched controls and whole blood from 645 AD patients and a...

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Literature Corpus work
fb7dd143-d240-5e51-a38c-91a79e11c3d7
DOI
10.1101/2020.04.24.060558
Open publication

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Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women with Alzheimer’s DiseaseDOI 10.1101/2020.04.24.060558
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