Article
Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women with Alzheimer's Disease
2020-05-22
Abstract excerpt
<title>Abstract</title> <p><bold>Background:</bold> Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the United States. In spite of evidence of females having a greater lifetime risk of developing Alzheimer’s Disease (AD) and greater apolipoprotein E4-related (apoE4) AD risk compared to males, molecular signatures underlying these findings remain elusiv...
Topics
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- Alzheimer's disease research and treatments
- Bioinformatics and Genomic Networks
- Cholinesterase and Neurodegenerative Diseases
- Dementia and Cognitive Impairment Research
- Gene expression and cancer classification
- Neuroinflammation and Neurodegeneration Mechanisms
- Single-cell and spatial transcriptomics
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- e42b7fbf-94fb-54ff-8242-a6fc5e405b3b
- DOI
- 10.21203/rs.3.rs-29773/v1
