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Article

Distinct sex-specific DNA methylation differences in Alzheimer’s disease

15 Sept 2022

Abstract excerpt

BACKGROUND: Sex is increasingly recognized as a significant factor contributing to the biological and clinical heterogeneity in AD. There is also growing evidence for the prominent role of DNA methylation (DNAm) in Alzheimer's disease (AD). METHODS: We studied sex-specific DNA methylation differences in the blood samples of AD subjects compared to cognitively normal subjects, by performing sex-specific...

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PMID: 36109771
DOI: 10.1186/s13195-022-01070-z

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