Article
Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk
2015-10-13
Abstract excerpt
INTRODUCTION: Ebbert et al. reported gene-gene interactions between rs11136000-rs670139 (CLU-MS4A4E) and rs3865444-rs670139 (CD33-MS4A4E). We evaluate these interactions in the largest dataset for an epistasis study. METHODS: We tested interactions using 3837 cases and 4145 controls from ADGC using meta- and permutation analyses. We repeated meta-analyses stratified by APOEϵ4 status, estimated combined OR and popu...
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Identifiers and source
- Literature Corpus work
- fb62a5d7-ed2e-50d2-a4ce-0e693e7ed2f7
- DOI
- 10.1101/028951