Article

Characterization and application of hyperthermia-evoked seizures in a mouse model of focal cortical dysplasia

2025-12-22

Abstract excerpt

Rodent models of drug-resistant epilepsy are widely used to uncover mechanisms of seizures and to test the efficacy of treatments; however, the stochastic and relatively infrequent nature of spontaneous seizures in these models makes it challenging to observe and manipulate peri-ictal activity, and to rapidly screen therapeutics. As fever has been identified as a clinical seizure trigger, we investigated the abili...

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Literature Corpus work: fb36120e-2d9a-5f41-9480-81d6771ba1a4
DOI: 10.64898/2025.12.19.695581

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