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Article

Daily Brief Heat Therapy Reduces Seizures in A350V IQSEC2 Mice and Is Associated with Correction of AMPA Receptor-Mediated Synaptic Dysfunction.

International journal of molecular sciences - 15 Feb 2023

Jada Reem, Borisov Veronika, Laury Eliezer, Halpert Shmuel, Levy Nina S, Wagner Shlomo, Netser Shai, Walikonis Randall, Carmi Ido, Berlin Shai, Levy Andrew P

Abstract excerpt

Purposeful induction of fever for healing, including the treatment of epilepsy, was used over 2000 years ago by Hippocrates. More recently, fever has been demonstrated to rescue behavioral abnormalities in children with autism. However, the mechanism of fever benefit has remained elusive due in large part to the lack of appropriate human disease models recapitulating the fever effect. Pathological mutations in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36835332
DOI: 10.3390/ijms24043924
PMCID: PMC9965438

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