Article
GABRG2 Deletion Linked to Genetic Epilepsy with Febrile Seizures Plus Affects the Expression of GABAA Receptor Subunits and Other Genes at Different Temperatures.
Neuroscience - 1 Jul 2020
Li Xinxiao, Guo Shengnan, Liu Kunmei, Zhang Chun, Chang Haigang, Yang Weilong, Rong Shikuo, Hu Qikuan, Cui Jianqi, Wang Feng, Sun Tao
Abstract excerpt
Mutations in γ-aminobutyric acid A receptor (GABAA) subunits and sodium channel genes, especially GABRG2 and SCN1A, have been reported to be associated with febrile seizures (FS) and genetic epilepsy with febrile seizures plus (GEFS+). GEFS+ is a well-known family of epileptic syndrome with autosomal dominant inheritance in children. Its most common phenotypes are febrile seizures often with accessory afebrile...
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