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Article

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy.

Journal of visualized experiments : JoVE - 12 Jul 2021

Das Antara, Smith Martin A, O'Dowd Diane K

Abstract excerpt

Transgenic mouse models have proved to be powerful tools in studying various aspects of human neurological disorders, including epilepsy. The SCN1A-associated genetic epilepsies comprise a wide spectrum of seizure disorders with incomplete penetrance and clinical variability. SCN1A mutations can result in a large variety of seizure phenotype ranging from simple, self-limited fever-associated febrile seizures...

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Identifiers

PMID: 34309607
DOI: 10.3791/62846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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