Article

Investigation of immunogenetic risk factors for carbamazepine-induced hypersensitivity reactions

2014-01-01

Abstract excerpt

T-cell mediated hypersensitivity reactions (HSRs) to carbamazepine (CBZ), a commonly used anti-epileptic drug, occur only in a small proportion of patients, but can often be severe in nature. As the underlying pathomechanisms are not fully understood, it has proven difficult to predict who may be at risk of developing CBZ-induced HSRs. Recently, specific human leukocyte antigen (HLA) alleles have been identified a...

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Literature Corpus work: fb35a8b6-88e4-58a0-a7fb-46157b9f6438
DOI: 10.17638/00019333

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