Article
HLA alleles and hypersensitivity to carbamazepine: an updated systematic review with meta-analysis.
Pharmacogenetics and genomics - 1 Feb 2014
Grover Sandeep, Kukreti Ritushree
Abstract excerpt
OBJECTIVE: A considerable heterogeneity exists in the literature on the role of different HLA alleles in carbamazepine (CBZ)-induced cutaneous adverse drug reactions (cADRs) of varying severity among diverse ethnic groups. The aim of the present study was to understand and summarize this heterogeneity and evaluate the contribution of common HLA alleles to susceptibility to cADRs in patients treated with CBZ...
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