Article
Human leukocyte antigens and drug hypersensitivity.
Current opinion in allergy and clinical immunology - 1 Aug 2007
Chung Wen-Hung, Hung Shuen-Iu, Chen Yuan-Tsong
Abstract excerpt
PURPOSE OF REVIEW: The present article reviews the recent literature on the identification of human leukocyte antigen (HLA) alleles as major susceptible genes for drug hypersensitivity and discusses the clinical implications. RECENT FINDINGS: Several recent studies have reported strong genetic associations between HLA alleles and susceptibility to drug hypersensitivity. The genetic associations can be drug...
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