Article

The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from Males

2022-11-09

Abstract excerpt

<h4>Background</h4> Cancer-cachexia (CC) is experienced by 80% of cancer patients, representing 40% of cancer-related deaths. Evidence suggests biological sex dimorphism is associated with CC. Assessments of the female transcriptome in CC are lacking and direct comparisons between biological sex are scarce. The purpose of this study was to define the time course of LLC-induced CC in females using transcriptomics,...

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Literature Corpus work: fb1234e4-063f-53e4-b14b-0d75b32fd443
DOI: 10.1101/2022.11.08.515691

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