Article

Anatomical dynamics define cancer cachexia subtypes and identify systemic inflammation as a marker of lethal wasting

2026-05-05

Abstract excerpt

Cancer cachexia is a wasting syndrome that remodels the anatomy of the patient. How this remodeling unfolds across tissues, whether it defines distinct disease states, and how these states relate to underlying biology remain unknown. We used longitudinal computed tomography imaging from 4,516 patients to quantify evolution of muscle, adipose, and organs during cachexia. Across two independent institutional cohorts...

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Literature Corpus work: 3ef64927-5d19-5fb3-86e8-a45ee4cb107a
DOI: 10.64898/2026.05.04.26352250

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