Article

Biological Sex Differences of Fibrosis During the Development of Cancer Cachexia

2023-01-04

Abstract excerpt

AIM Cachexia is characterized by losses in lean body mass and its progression results in worsened quality of life and exacerbated outcomes in cancer patients. However, the role and impact of fibrosis during the early stages and development of cachexia in under-investigated. The purpose of this study was to determine if fibrosis occurs during cachexia development, and to evaluate this in both sexes. <h4>Methods: <...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6ff9a095-3d77-5f47-9d6e-3d9591a578d2
DOI: 10.22541/au.167285880.01226764/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Biological Sex Differences of Fibrosis During the Development of Cancer CachexiaDOI 10.22541/au.167285880.01226764/v1Read

The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from MalesSemantic proximity Read

The time-course of cancer cachexia onset reveals biphasic transcriptional disruptions in female skeletal muscle distinct from malesSemantic proximity Read

Progressive development of melanoma-induced cachexia differentially impacts organ systems in miceSemantic proximity Read

Transcriptomic analysis of the development of skeletal muscle atrophy in cancer-cachexia in tumor-bearing miceSemantic proximity Read

Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemiaSemantic proximity Read

Cancer cachexia-induced muscle atrophy: evidence for alterations in microRNAs important for muscle sizeSemantic proximity Read

Sexual Dimorphism of Skeletal Muscle in a Mouse Model of Breast Cancer: A Functional and Molecular AnalysisSemantic proximity Read

A Multiomic Analysis of Cachectic Mice Reveals Cancer Driven Suppression of Muscle Stem Cell DifferentiationSemantic proximity Read

Anatomical dynamics define cancer cachexia subtypes and identify systemic inflammation as a marker of lethal wastingSemantic proximity Read

Toll-Like Receptor-4 Disruption Suppresses Adipose Tissue Remodeling and Increases Survival During Cancer Cachexia SyndromeSemantic proximity Read

Distinct cachexia profiles in response to human pancreatic tumours in mouse limb and respiratory muscleSemantic proximity Read

Early adipose tissue wasting in a novel preclinical model of human lung cancer cachexiaSemantic proximity Read