Article

Relevance of cancer cachexia models – muscle whole genome gene expression in human and animal cachexia

2020-10-26

Abstract excerpt

<title>Abstract</title> <p>BackgroundCancer cachexia is a complex and multi-factorial syndrome. As currently available therapeutic options are limited, more in-depth knowledge on cachexia pathophysiology and the underlying molecular mechanisms remains warranted. Studies with animal models provide useful insights but they only mimic the human situation to a certain degree. Furthermore, there is heterogeneity in th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: db833f3e-fd36-5ad2-ab49-be6d3410611a
DOI: 10.21203/rs.3.rs-56696/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Relevance of cancer cachexia models – muscle whole genome gene expression in human and animal cachexiaDOI 10.21203/rs.3.rs-56696/v1Read

Distinct cachexia profiles in response to human pancreatic tumours in mouse limb and respiratory muscleSemantic proximity Read

The Pathway to Cancer Cachexia: MicroRNA-Regulated Networks in Muscle Wasting Based on Integrative Meta-AnalysisSemantic proximity Read

Transcriptome and microRNAome profiling of human skeletal muscle in pancreatic cancer cachexiaSemantic proximity Read

Mitochondrial dynamics in cancer-induced cachexiaSemantic proximity Read

An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent modelsSemantic proximity Read

MicroRNA-mRNA Co-sequencing Identifies Transcriptional and Post-transcriptional Regulatory Networks Underlying Muscle Wasting in Cancer CachexiaSemantic proximity Read

Specific miRNAs are associated with human cancer cachexia in an organ‐specific mannerSemantic proximity Read

Cancer cachexia-induced muscle atrophy: evidence for alterations in microRNAs important for muscle sizeSemantic proximity Read

Progressive development of melanoma-induced cachexia differentially impacts organ systems in miceSemantic proximity Read

The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from MalesSemantic proximity Read

Identification of microRNAs in skeletal muscle associated with lung cancer cachexiaSemantic proximity Read

Transcriptomic analysis of the development of skeletal muscle atrophy in cancer-cachexia in tumor-bearing miceSemantic proximity Read